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Khellin has antispasmodic and coronary vasodilator effects
InChiKey: JDQOICVJUDEXEQ-UHFFFAOYSA-N
InChi: InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H
130 nM and 360 nM for JIMT-1
It has >100-fold selectivity over other methyltransferases and other non-epigenetic targets
Galiellalactone apazamine Khellin has antispasmodic and coronaryGaliellalactone is a is a small non toxic and non mutagenic fungal metabolite, a selective inhibitor of STAT3 signaling, with an IC50 of 250 500 nM. Galiellalactone can be used to research castration resistant prostate cancer. Product information CAS Number: 133613 71 5 Molecular Weight: 194. 23 Formula: C11H14O3 Chemical Name: (4R, 7R, 9S, 11S) 11 hydroxy 9 methyl 3 oxatricyclo[5. 3. 1. 0, ]undec 1(10) en 2 one Smiles:
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